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What are the side effects of budesonide
Budesonide is part of a group of drugs called corticosteroids which acts directly on the airways to reduce the inflammation levelsin the airways and reduce the production of certain drugs which cause asthma-like symptoms.The drugs have been shown through animal studies to be highly effective in the reduction of allergic symptoms, with patients being able to go without asthma or breathlessness for weeks or even months, over the counter steroids pills.However it is unknown whether Budesonide can also exert its anti-inflammatory effect on the airways without exacerbating a number of other symptoms, oral corticosteroids budesonide.For this reason, research by the University of Glasgow is currently evaluating the safety and efficacy of Budesonide in treating asthma, both as part of the anti-inflammatory regimen provided to patients and also to assess whether the drug might also have a positive effect on breathing.The study, led by Dr Emma MacLeod, is available for research at the UK-based journal Clinical Immunology and will be published in December next year, over the counter medicine for laryngitis.The research looked at the effects of Budesonide on the immune system and airway inflammation which are key factors in asthma.The researchers found that Budesonide, an organic chemical produced by many plants, was able to reduce the levels of two important anti-inflammatory drugs, interleukin-6 (IL-6) and tumour necrosis factor alpha (TNF-alpha).They also found that the drug reduced the amount of a third, chemosensory receptor agonist, L-arginine, which is an essential component of the asthma fight-or-flight response, oral budesonide corticosteroids.The researchers said: "Although the antiinflammatory effects of Budesonide were dose-dependent, the lowest dose of 10mg provided an overall increase in TNF-alpha production, and was capable of stimulating the activity of IL-6, IL-6-induced TNF-alpha production, and IL-6 and TNF-alpha production, in all healthy volunteers, as well as those with normal asthma."They also found that the anti-inflammatory effect of Budesonide, as compared to conventional anti-allergy treatments in humans, was likely to be related to a greater impact on the inflammation levels.The researchers said: "Budesonide reduced IL-6 and IL-6's ability to stimulate IL-6 expression in the lungs in a dose-dependent manner and also reduced IL-6-regulated levels of TNF-alpha in healthy volunteers, which was a result of improved immune tolerance in those exposed to Budesonide, over the counter steroids to build muscle."